Pandemic Flu: Preparing and Protecting against Avian Influenza



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Pandemic Flu: Preparing and Protecting against Avian Influenza

The most famous and lethal outbreak was the so-called Spanish flu pandemic (type A influenza, H1N1 subtype), which lasted from 1918 to 1919. Older estimates say it killed 40–50 million people while current estimates say 50 million to 100 million people worldwide were killed. This pandemic has been described as "the greatest medical holocaust in history" and may have killed as many people as the Black Death. This huge death toll was caused by an extremely high infection rate of up to 50% and the extreme severity of the symptoms, suspected to be caused by cytokine storms. Indeed, symptoms in 1918 were so unusual that initially influenza was misdiagnosed as dengue, cholera, or typhoid. One observer wrote, "One of the most striking of the complications was hemorrhage from mucous membranes, especially from the nose, stomach, and intestine. Bleeding from the ears and petechial hemorrhages in the skin also occurred." The majority of deaths were from bacterial pneumonia, a secondary infection caused by influenza, but the virus also killed people directly, causing massive hemorrhages and edema in the lung.

Pandemic Flu: Preparing and Protecting against Avian Influenza

[1] Due to ongoing scientific and policy analyses, the deadlines for 14 actions ... President | Vice President | First Lady | Mrs. Cheney | News & Policies ...

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Pandemic flu : Department of Health

... NHS preparedness and to reduce the impact of pandemic flu ... Policy and guidance. Publications and statistics. News. Consultations. Procurement and proposals ...

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PandemicFlu.gov

Official U.S. government Web site for information on pandemic flu and avian influenza.

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Planning for Pandemic Flu

Policy Service. Policy Alert. Planning for Pandemic Flu. February 2007 ... Using a past pandemic as a guide, the events during the flu outbreak of 1918 ...

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Health & Safety

Pandemic and avian flu information for individuals, families, travelers, workers, and health care professionals ... Privacy Policy. Web Site Disclaimers. White ...

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CIDRAP >> Pandemic Influenza

A seven-part series on the chances for immunizing the world against pandemic flu ... Center for Infectious Disease Research & Policy ...

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Pandemic Flu Leadership Blog : May 22 - June 27, 2007 " Comment Policy

U.S. leaders discuss pandemic flu preparedness during HHS' blog summit ... The purpose of this blog is to discuss preparation for a potential flu pandemic. ...

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Pandemic Influenza

... Reports Federal Pandemic Flu Web site Contacts EP&R Home Epidemiology Home ... Home | Employment | Contact Us | FOIA Policy | Search ...

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Ohio Pandemic Influenza

... webmaster privacy policy publication library. Files ... Ohio Department of Health Pandemic Flu Plan. Dept. of Agriculture. Spread the Message Campaign ...

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Pandemic Flu

Pandemic Flu information from the Massachusetts Department of Public Health ... © 2002 The Massachusetts Department of Public Health Privacy Policy Contact Us ...

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Pandemic Flu: Preparing and Protecting against Avian Influenza

Vaccinations against influenza are most commonly given to high-risk humans in industrialized countries and to farmed poultry. The most common human vaccine is the trivalent flu vaccine that contains purified and inactivated material from three viral strains. Typically this vaccine includes material from two influenza A virus subtypes and one influenza B virus strain. A vaccine formulated for one year may be ineffective in the following year, since the influenza virus changes rapidly over time and different strains become dominant. Antiviral drugs can be used to treat influenza, with neuraminidase inhibitors being particularly effective.

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